Ketone bodies can help address diminished cerebral glucose metabolism (DCGM) in Alzheimer’s disease1-3
Ketone bodies are naturally produced by the liver as a back-up fuel when glucose levels are low.1 Ketone body metabolism has a number of advantages that lead to increased metabolic efficiency in cerebral mitochondria.4
In Alzheimer’s disease and preclinical models, raised ketone body levels protect against amyloid-β toxicity and deposition in vitro and provide cognitive benefits in vivo.5-7 These properties make ketone bodies an attractive means to address DCGM in Alzheimer’s disease.
Ketone bodies: the brain’s natural back-up fuel1,3
Find out how Axona can help during times of DCGM.