ROLE OF METABOLISM

Metabolism is the process that makes energy available to the body. The human brain is one of the most metabolically active organs in the body, and under normal circumstances, it relies almost exclusively on glucose as its source of energy. The real work of the brain goes on in the cells—about 100 billion nerve cells (neurons) that connect at more than 100 trillion points with branches.

Memories, thoughts, and feelings are created by the signals that travel through this amazing network. The normal, healthy brain depends on circulating glucose for most of its functions. In Alzheimer's disease, glucose is poorly utilized by nerve cells and brain function is decreased. Science has shown that a drop in glucose use in certain areas of the brain may start 10 to 20 years before any symptoms of Alzheimer's appear.

Deprived of glucose, their primary source of energy, these brain cells don't function well. By introducing an alternative source of energy to nerve cells, it may be possible to improve brain activity and cognitive function, thus lessening the devastating effects of Alzheimer's disease and helping to manage the disease. Axona works by supplying an alternative source of energy, or fuel, to brain cells.